The dual-effect risk loci also include the region covering the gene FABP4, which is already being investigated for its potential as a diabetes and heart-disease drug target. In mouse studies, inhibition of this gene's protein has been shown to have anti-atherosclerotic, i.
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Saleheen, co-senior author Benjamin F. Voight, PhD, an associate professor of Genetics, and their colleagues now plan further investigations of the dual-risk genes uncovered in the study. The researchers also hope to learn more about the biology of the newly discovered dual-risk genes by studying people who have mutations in those genes, Saleheen said. Materials provided by University of Pennsylvania School of Medicine.
Note: Content may be edited for style and length. Science News. Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Nature Genetics , ; DOI: ScienceDaily, 4 September University of Pennsylvania School of Medicine.
Diabetes and heart disease linked by genes, reveals study: Gene variants that boost the risk for both diseases may be targets for future therapies. Retrieved September 24, from www. New research shows that a high-fat, low-carb Below are relevant articles that may interest you. ScienceDaily shares links with scholarly publications in the TrendMD network and earns revenue from third-party advertisers, where indicated.
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Genetic causes of type 2 diabetes
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